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However, similar to the plant defensin ApDef136 we also observe some intracellular effects, suggesting multiple targets of this compound.
By analyzing multiple targets of the same sample material an uncertainty level of 0.3% has been reached.
From there, the hackers moved on to hit multiple targets of varying fame: US broadcaster PBS, where they planted a fake story saying the dead rappers Tupac Shakur and Biggie Smalls were in fact alive and living in New Zealand.
Work to identify the multiple targets of miRNAs is still in its infancy, and a clear distinction between siRNAs and miRNAs is difficult in some instances.
Results from a mine tailings site demonstrate the approach performs reasonably well for highly complex landscape with multiple targets of various sizes and shapes.
We applied theory on dual allegiance to multiple targets of commitment, in conjunction with person-organization fit theory, to explore the dynamics of organizational and professional commitment among scientists and engineers working in hybrid, research-focused organizations.
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Previous study have shown that signal peptide which helps to direct the target protein into subcellular compartments may be masked by the target protein itself, and thus causes mis-targeting or multiple targeting of the protein (Tanz et al. [2013]).
This raises the possibility of multiple targets on each trial.
The data also allow to identify the target promiscuity of the NCE e.g. described for the multiple targeting of the anti-cancer drug Imatinib (Gleevec) or the schizophrenia drug Clozaril [15].
In addition to the multiple targeting of the HIV-Gag p17 region, subject OP428 had a CTL response towards an HLA-A2-restricted epitope in the RT region of HIV-Pol, RT 33-41 (Table 6).
These could be the result of a multiple targeting of different pathways on endothelial cells as well as on tumor cells.
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