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Preclinical research has identified multiple targets affecting remyelination in experimental animal models of demyelinating disease, and early stage human clinical trials have started.
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The body of literature clearly demonstrates multiple targets affected by low doses of BPA, including metabolism, especially when the exposure occurs at critical periods of development (Vandenberg et al. 2012).
The propolis extract present a multitude of constituents that can act on multiple biochemical targets affecting the balance of complex cellular networks in a way that is currently not fully understood such as the multi target efficacy model proposed by CSERMELY et al. [2].
These phytochemicals exert their anticancer effects through modulation of multiple molecular targets affecting various signaling pathways [ 8, 14, 15].
Diseases are usually multifactorial, in which multiple targets are affected and have to be targeted for successful treatment outcomes.
It was demonstrated that miR-146a regulates multiple targets to affect different aspects of the central network.
(b) Functional drug target prediction using network-based recommendation Drugs often have multiple targets and affect distinct signaling modules, but only parts of them are known for given drugs.
Evaluate the multiple end-organ targets affected by intradermal testing (IDT -based IDT -basedapy.
MiR-29 has multiple targets that may affect neuronal growth (Govek et al., 2005; Wang et al., 2013).
NO could either affect bacterial viability directly by affecting multiple targets such as mycobacterial DNA and copper metabolism [41] [43], target mycobacterial virulence factors [23] or act as second messenger [24].
We used the Multiple Object Tracking (MOT) paradigm to explore whether the high-level biological status of the targets affects the efficiency of attentional selection and tracking.
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CEO of Professional Science Editing for Scientists @ prosciediting.com