Sentence examples for multiple targeted inhibitors from inspiring English sources

Furthermore, these data not only offer a potential explanation for the clinical failure of trastuzumab treatment despite confirmed HER2 overexpression, but also implicate particular subsets of HER2-positive breast cancer patients as candidates for combination drug therapy employing multiple targeted inhibitors of aberrant signaling mediated by HER2, HER3, and/or p95.

ErbB3-mediated signaling was identified as a potent mechanism of resistance to multiple targeted agents, and combining the ErbB3 inhibitor MM-111 with ErbB2 inhibitors was found to induce synergistic tumor regression.

"There are very few specific or targeted inhibitors that are used in the treatment of brain cancer.

Tallman believes that the next step in treatment should involve combining AG-221 with a chemotherapy drug, as well as with other targeted inhibitors of gene mutations, or with bone-marrow transplantation.

Finally, she received a targeted inhibitor of ALK.

Not all EGFR-expressing cancers respond to targeted inhibitor treatment.

A final parameter, K B, applied to the targeted inhibitor.

This knowledge has led to numerous treatment strategies combining endocrine and targeted inhibitor therapies.

The receptor AXL diversifies EGFR signaling and limits the response to EGFR-targeted inhibitors in triple-negative breast cancer cells.

I focused on these two hallmarkers to design the dual-targeted inhibitors for cancer therapy.

Drug screening showed these triple-negative cancers to be sensitive to eEF2K-targeted inhibitors.