Sentence examples for multiple targeted combinations from inspiring English sources

In conclusion, this study utilises a molecular selection approach in expansion cohorts to obtain additional safety and preliminary efficacy data, in order to facilitate developmental decisions for multiple targeted combinations.

Intra-tumor heterogeneity also makes a strong case for the use of multiple targeted therapies in combination regimes [253].

This may be particularly relevant to efforts to improve trial efficiency in order to test multiple targeted new agents in combination.

The need to test multiple new targeted agents both alone and in combination with other targeted therapies, as well as classic cytotoxic agents, demands the development of novel therapeutic platforms (particularly Master Protocols) capable of efficiently and effectively testing multiple targeted agents or targeted therapeutic strategies in relatively small patient subpopulations.

Morphoproteomics can potentially identify targeted combinations of drugs appropriate for prospective testing [9].

Multiple-targeted ligands can have certain advantages for the management of hypertension which has multiple controls.

Different mental disorders are linked to violence via different core explanations, suggesting multiple-targeted prevention strategies.

Targeted anticancer treatments are an important and evolving new approach to cancer therapy and, in order to treat tumours with defects in multiple oncogenic pathways, combinations of targeted agents are being actively investigated.

Development of an efficient modelling and simulation of the response of signalling protein phosphorylation on multiple, complex combinations of stimuli and inhibitors is crucial for improved research for targeted drugs and may play an important role in systematic development of direct reprogramming of cells in future.

Experiment with multiple weapon combinations.

Therefore, the multi-targeted approaches are anticipated through either combination of selectively defined agents or by a single agent with multiple targets.