Multiple non-targeted biopsies also add to the cost and the time it takes to perform the procedure, without necessarily improving the diagnostic yield.
The limitations of TRUS-guidance for lesion detection during targeted biopsies should be acknowledged in order to improve the diagnostic yield of targeted biopsies.
"We can now pinpoint prostate cancers using MRI (magnetic resonance imaging) scans and targeted biopsies, allowing a much more targeted approach to diagnosis and treatment.
Magnetic resonance imaging (MRI) and targeted biopsies (TB) have shown potential to more accurately detect significant prostate cancer compared with prostate-specific antigen (PSA) and systematic biopsies (SB).
The histological results from standard biopsies were upgraded on targeted biopsies in 8 of 10 cases.
Results after targeted biopsies were Gleason 4 + 3 = 7 tumour with two out of three core biopsies in the left middle lateral PZ sextant.
7– 10 Therefore, random biopsies are recommended in addition to targeted biopsies of suspicious lesions.
All men received a saturation biopsy (SB) in addition to targeted biopsies of lesions with PIRADS≥2.
In-bore MR-guided biopsies were the first targeted biopsies performed using MRI-identified lesions.
Moreover, the total detection rate for five targeted biopsies alone was higher than for 10 random biopsies (Figs. 1 4).
