Multiple, as well as more targeted approaches may be required before all gene products involved in responses to infection with Plasmodium are identified.
Understanding the dynamics of the EGFR, Src and Stat3 molecular interactions in pancreatic cancer would provide basis to design novel effective multiple-targeted therapy approaches for pancreatic cancer.
In contrast to the multiple analysis of one control sample as performed in targeted approaches, control samples from a representative number of individuals in a trial need to be included for this type of quality control.
Tomorrow's therapies are likely to involve more targeted approaches.
Make targeted approaches to smaller companies through a named person via a well-timed phone call.
Priority should be given to developing more targeted approaches.
Additional targeted approaches are therefore urgently needed.
Further accuracy is introduced by "targeted" approaches.
In conclusion, this study utilises a molecular selection approach in expansion cohorts to obtain additional safety and preliminary efficacy data, in order to facilitate developmental decisions for multiple targeted combinations.
Development of less-toxic, targeted approaches is clearly necessary.
