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Here, we expand on the previous analysis by performing more pathway and functional analyses in order to develop a more efficient strategy for multiple target therapy.
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To discuss the role of clinical trials in the changing landscape of cancer care resulting in individualized cancer treatment plans including a discussion of several innovative randomized studies designed to evaluate multiple targeted therapies in molecularly defined subsets of individuals.
Nanomedicine-based combination anticancer therapy can synergistically improve antitumor outcomes through multiple-target therapy, decreasing the dose of each therapeutic agent and reducing side effects.
Based on these achievements, we present the first attempt to combine multiple-target therapy with systems biology.
As the first trial to develop multiple-target therapy, cancer house-keeping proteins (common core network markers) may be a good choice.
Based on these results, wet-lab bio-scientists could freely investigate combinations of these drugs for multiple-target therapy for cancers, in contrast to the traditional single target therapy.
BD offers a multiple target regimen in cancer therapy.
In contrast to traditional single target therapy, we used multiple-target cocktail therapy to attack common core network markers, i.e., to inhibit several key proteins simultaneously instead of inhibiting only one single target.
Multiple Target Ligands.
Multiple Target Ligand Database.
miRNA-based therapy may have some advantages compared with that for other molecular targets because one endogenous miRNA can target its multiple target genes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com