Ai Feedback
Exact(4)
In the analysis of the number of miRNAs with perfect seed matches to Alu consensus and randomized Alu sequences, multiple target site predictions in the same sequence were counted as only one prediction.
In the analysis of the number of target sites per miRNA, multiple target site predictions in the same sequence were counted as separate hits, and the total number of hits for each miRNA seed was normalized per megabase of sequence.
These include base pairing pattern, thermodynamic stability of the miRNA mRNA duplex [20], comparative sequence analysis of target sites in different species, multiple target site evaluation, site accessibility and UTR context [20 22].
Given that 3′ UTRs can contain multiple target site copies for a single miRNA, the target accessibility of the entire UTR for a given miRNA was calculated according to the formula ΔΔ G Score = 1 n ∑ 1 n e − ΔΔ G n [ 67].
Similar(56)
Analyses carried out suggest that multiple phytotoxic compounds in the leachate may be acting in concert to compromise multiple target sites at the cellular level.
In addition, precautionary approaches are needed to minimize risks of translocation failures (maladaptation) that can be reduced through redundancy of multiple target sites.
These discharges contain a mixture of organic and inorganic contaminants that may cause multiple biological effects (e.g., estrogenic, genotoxic, cytotoxic, or carcinogenic effects) due to interactions with multiple target sites in the exposed organisms [2, 3].
Among the numerous candidate regulatory miRNA of CDK6, we selected miR-29b for further investigation because we only focused on miRNAs that had multiple target sites within the 3′-UTR of CDK6.
The phytochemical biomolecules could be used for maximizing the effectiveness and specificity in future insecticide design with specific or multiple target sites, while ensuring the economic and ecological sustainability.
John and Marks [15] proposed that miRNAs may act cooperatively through multiple target sites in one gene.
Multiple target sites within the same sequences at different positions were allowed.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com