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Some CB2-R immunoreactive dendrites were seen to receive multiple synaptic contacts from axon terminals lacking CB2-R-IR (Fig. 8A).
The terminal boutons are also unusual in that they are densely packed with vesicles and make multiple synaptic contacts with the post-synaptic cell [60].
Although it was not possible to estimate the electrotonic distance between the synapses and their total number, or to attribute the groups of synapses to the components of a composite EPSC, the labelling experiments suggested that multiple synaptic contacts between an SG EIN and a postsynaptic neuron can form the anatomical basis for the composite EPSCs.
Inside a glomerulus, the claw-footed dendrites of granule cells wrap around and make multiple synaptic contacts with the single, large, mossy fiber termination.
In contrast, the IPSCs examined here were mediated by multiple synaptic contacts of FS basket cells on L5 CCS pyramidal cells.
They also expressed markers implying neurotransmitter synthesis, such as GABA-synthesising enzyme and glutamic acid decarboxylase; and they made multiple synaptic contacts, suggesting the GFP-expressing Purkinje cells were at least functional.
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Multiple synaptic boutons contacting the target muscle cell are visible as yellow varicosities (scale bar = 10 μm).
In addition, a significant number of PC spines lack synaptic contacts with PF terminals and multiple climbing fiber (CF) innervation to PCs is sustained in GluRδ2 mutant mice [13], [16] [18].
Electrical synaptic contacts could be formed at multiple central cellular compartments including somatic, and proximal dendritic and axonal sites according to previous studies on gap junctions of excitatory neurons [39], [40], [41].
Disturbed cerebellar development typically yields multiple weak CF inputs that fail to form strong one-to-one multisite synaptic contacts with the PC [22].
Multiple nuclei, including the neuroendocrine magnocellular and parvocellular nuclei, regulate complex processes through direct synaptic contacts as well as release into tissues and portal systems (Garcia-Segura, 2009; Machluf et al., 2011).
More suggestions(15)
multiple synaptic components
multiple synaptic pathways
multiple VGlut1+ contacts
multiple additional contacts
multiple daily contacts
multiple hydrophobic contacts
multiple concurrent contacts
multiple discrete contacts
multiple direct contacts
multiple focal contacts
multiple initial contacts
multiple synaptic transmissions
multiple synaptic boutons
multiple synaptic inputs
multiple synaptic clefts
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