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Moreover, the tiniest babies born at the limit of viability often require multiple surfactant administrations.
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The results may be important in understanding inhibition of lung surfactants by serum proteins and in designing efficient protocols of surfactant preparation and administration.
Li X, Cheng T, GuanR, Liang H, Lu WN, Zhang JH, et al. Effects of different surfactant administrations on cerebral autoregulation in preterm infants with respiratory distress syndrome.
European perspective on less invasive surfactant administration—a survey.
Less invasive surfactant administration (LISA) uses a thin catheter inserted into the trachea to deliver the surfactant.
Early surfactant administration with brief ventilation vs. selective surfactant and continued mechanical ventilation for preterm infants with or at risk for respiratory distress syndrome.
Survey shows large differences between the Nordic countries in the use of less invasive surfactant administration.
Niemarkt HJ, Kuypers E, Jellema R. Effects of less-invasive surfactant administration on oxygenation, pulmonary surfactant distribution, and lung compliance in spontaneously breathing preterm lambs.
The neonatologist present at the delivery treated the infant with intubation, surfactant administration, and blood transfusions, after which she was transferred to the NICU.
Kanmaz HG, Erdeve O, Canpolat FE, Mutlu B, Dilmen U. Surfactant administration via thin catheter during spontaneous breathing: randomized controlled trial.
A pilot study of less invasive surfactant administration in very preterm infants in a Chinese tertiary center.
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