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Ex vivo PBMCs were stained for multiple surface markers to characterize CD4+CD8+ T lymphocytes.
Previous reports have shown the use of multiple surface markers to identify NSCs based on a CD184+CD271-CD44-CD24+ staining signature (Yuan et al., 2011).
Cell sorting based on multiple surface markers such as CD25, CD127, CD62L and CD27 yields a high purity of FoxP3pos Treg.
Thus, low-grade glioma cells may resemble the expansion of A2B5+ glial progenitor-like cells; high-grade gliomas, in addition to the expansion of A2B5+ glial progenitor-like cells, may also contain CD133+ putative glioma stem cells that concomitantly express multiple surface markers of glial progenitor cells.
NPS is a simple, yet accurate method to screen cells for multiple surface markers simultaneously.
Third, one can use a single agent to target multiple surface markers that are differentially expressed on cancer cells with progression of the disease.
Similar(49)
It is well known that DCs express multiple surface phenotype markers which are closely related to DCs' functions and maturation process [6, 33, 34].
Our data show that nearly all low-grade glioma cells from the analyzed cases concomitantly express multiple cell surface markers for glial progenitor cells, such as PDGFRα, A2B5, O4, and CD44.
In this study, we investigated the expression of multiple cell surface markers characteristic of glial genesis hierarchy in freshly isolated viable glioma cells as well as the expression of GFAP, NSE and synaptophysin in the fixed specimens from a cohort of low-grade and high-grade glioma patients.
Flow cytometry is known as an excellent phenotyping tool, because multiple molecules, surface markers as well as intracellular proteins, can be detected in individual cells [ 6].
Performing large numbers of functional screens using different combinations of multiple cell surface markers is virtually impossible because stem cell transplantation is required to validate stem cell function.
More suggestions(15)
multiple surface morphemes
multiple surface loads
multiple surface gateways
multiple surface fillings
multiple surface antigens
multiple surface devices
multiple surface cracks
multiple surface groups
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multiple surface proteins
multiple surface sites
multiple surface pre-cracks
multiple surface patches
multiple surface receptors
multiple surface energies
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