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These versatile carriers have multiple surface groups that can be functionalized with imaging agents, drugs, labels, and targeting ligands.
Multiple surface groups on dendrimers can be linked with polymers, 25) amino acids, 26) tissue targeting moieties, drugs, nucleic acid molecules, 32) or imaging agents 33) to modulate properties of the dendrimer-based drug or imaging agent carriers.
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(A) Dendrimers with multiple surface functional groups can be directed to cancer cells by tumor-targeting entities that include folate or antibodies specific for tumor-associated antigens (TAAs).
However, recent studies by our group have documented the presence of toxigenic V. cholerae O1 at multiple surface water sampling sites, 7 suggesting that reliance on surface water for drinking is not optimal and should be actively discouraged.
Figure 1 Using multiple surface gateways.
Adsorption experiments showed features suggesting multiple surface energies.
Multiple surface cooling devices were used in 32 patients.
SOUTHAMPTON "Shaping the Surface," group show.
WASHINGTON DEPOT "On the Surface, Below the Surface," group show.
A multiple-site surface, such as the pyrite surface, offers the possibility to bind species that are chemically different; one species binding to the thiol surface group, the other binding to the iron surface group.
The Surface lends itself to social activities around a table, and you could even connect multiple Surfaces over the net.
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