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52 While differences between these subgroups were significant, the results might be a statistical artefact; it is possible that small frequent doses will lead to large reductions in mortality, but it seems unlikely that a single supplement is more effective than multiple supplements of the same dose.
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If the above criteria failed to produce adequate data, we planned to include data from quasi-randomised trials, trials without placebo control and trials of multiple supplements, with appropriate caution in the interpretation of such data.
Our results help to explain the apparent increase in neonatal and perinatal mortality reported from other trials using the same or similar formulation of multiple micronutrient supplements compared with standard iron-folic acid supplements.
Don't Butme '2016' for Your Shitty Yeas.
We analyzed data from a randomized, controlled, double-blinded community-based trial of prophylactic zinc and multiple micronutrient supplements in the primary prevention of diarrhoea in three cohorts of children (Luabeya et al. 2007).
Although few of these studies applied synthetic medium [ 18, 19], the studied (auxotrophic) strains still required the addition of multiple medium supplements such as amino acids and nucleic bases.
Our findings indicate that daily use of multiple dietary supplements has no effect on arterial stiffness (i.e. pulse wave velocity and augmentation index), endothelial function (i.e. brachial artery flow-dependent vasodilatation) or blood pressure in nonobese men and women.
The absence of an impact on early or late infant survival concurs with the findings of trials of maternal vitamin A supplementation from Nepal 21 and Bangladesh 22 23 and a pooled meta-analysis of the effects of maternal multiple micronutrient supplements.
Of these, eighteen took multiple micronutrient supplements, eight took Fe and folate, and four took Fe.
23 These findings were interpreted by the authors as an increased risk of perinatal mortality with multiple micronutrient supplements.
Multiple micronutrient supplements (MMS) during pregnancy is one of the strategies to prevent adverse pregnancy outcomes (14, 15).
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