Sentence examples for multiple substitutions was from inspiring English sources

Kimura correction for multiple substitutions was applied [56].

Kimura correction for multiple substitutions was applied [ 33].

The Jukes-Cantor correction for multiple substitutions was applied.

The tree did not change considerably when a correction for multiple substitutions was applied, nor did it change when 10,000 replicates were used.

and (ii) the programs available in the ClustalW suite [ 23] (no correction for multiple substitutions was applied) where the distances are computed based on percent identity scores.

Homoplasy due to multiple substitutions was tested with the index of substitution saturation (ISS) [ 56, 57], which assumes a critical index of substitution saturation (ISSc) that defines a threshold for significant saturation in the data.

To investigate alternative mechanisms by which A8 substitutions enhance activity, multiple substitutions were introduced.

For calculating cooperativity, the effect of multiple substitutions is measured directly (observed value).

For a number of residues multiple substitutions were created, which almost in all cases produced the same effect.

The T184, S202 or M250 ETV signature substitutions did not display significant resistance in the absence of LVDr changes, establishing that multiple substitutions were required for phenotypic resistance leading to virologic breakthrough on ETV.

Multiple substitutions were corrected using the Poisson distance model.