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Since the observed substitution rates were different for each of the four nucleotides, we introduced corrections for multiple substitutions and reversions for each type of the substituted nucleotide instead of one general correction.
"Maybe for 15 or 20 minutes in the second half the game died a death a little, we both made multiple substitutions and then the pattern for both teams broke up a bit.
We chose to exclude regions of each gene that showed evidence of high levels of saturation by multiple substitutions, and poor sequencing quality from phylogenetic analyses.
trnV-UAC and trnP-UGG are putative pseudogenes since they differ from their orthologs by multiple substitutions and indels.
NJ trees were generated using ClustalX software (Larkin et al., 2007), correcting for multiple substitutions and bootstrapped by 1000 repetitions.
The region appears to have been further modified by multiple substitutions and indels since the conversion event.
Similar(39)
P-distances, 4 DTv (corrected for multiple substitution), and the dN/dS ratio (non-synonymous to synonymous substitutions using all codons) are shown in Table 1.
Hence, more evidence is needed to examine the economic impact of generic substitution in a real-life therapy situation, where chronic generic therapy may involve multiple substitution and thus multiple switching.
Three minutes later Thiago made it four, the multiple substitutions began and it threatened to get edgy as Argentina's frustration showed in their tackles, but Spain had still not finished.
Secondly, the jarosite structure can undergo multiple substitutions (Basciano and Peterson, 2008).
We also made other modifications accordingly, such as using κR and κY to estimate S and N, generating relevant transition probability matrix (equation 1), considering different transitional evolution pathways to count Sd and Nd, and correcting for multiple substitutions when estimating Ka and Ks (equation 4; [ 22]).
More suggestions(15)
multiple surrogates and
multiple changes and
multiple chins and
multiple commandos and
multiple campaigns and
multiple dogs and
multiple layers and
multiple calls and
multiple canoes and
multiple surgeries and
multiple hospitals and
multiple voices and
multiple cameramen and
multiple lacerations and
multiple controllers and
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com