Due to the fact that some articles might be classified under multiple subject areas (a feature of Scopus), we used different first pages for different subjects, to avoid the same article accidentally being included in several samples.
Integrate multiple subject areas.
In general, the quality control samples provided by each cohort's investigators were either pooled samples from multiple subjects or specimens from separate individuals that were repeated throughout that cohort's batches.
In order to explore the possibility of a common gene panel that can reliably detect cancer originated from multiple tissue types, we created a compendia of 5 microarray datasets from prostate, lung, ovarian, colon, and breast, respectively, each with cancer and normal samples from multiple subjects (Table 1).
This is a more practical setup, since in many computer vision datasets, e.g., for face alignment [31, 32], only static images of multiple subjects are provided, where only a few samples of the same subject is available.
Again, this explanation requires multiple subjects within several discreet sub-groups within this sample of 40 Caucasians which, although possible, seems less likely.
Our second contribution is about dealing with multiple subjects.
Where things could get really interesting is combining multiple subjects.
Schedule multiple subjects during each session.
In an 'omics global profiling experiment, multiple samples (subjects) will be analyzed and many molecules (observations) detected in each sample.
