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Of special interest were meta-analytic models for combining information from multiple studies involving interventions for the same condition.
Multiple studies involving the outcomes of anterior interbody cages have been published, but the majority were by authors who designed the cage.
These findings were quickly confirmed by multiple studies involving direct sequencing of IDH1 and its homologue IDH2.
However, given that multiple studies involving varying stavudine dose have found an association between higher weight or BMI and lactic acidosis [7], [11], [17] while, in some cases, controlling for dose [16], [18], it is unlikely that drug dosing explains the entire effect.
To date, no other coding region polymorphism analogous to a polymorphism associated with a genetic TSE in humans has been identified in cattle [12], [15], nor has this polymorphism been previously reported in any other cattle despite the sequencing efforts of multiple studies involving several thousand cattle.
Both abundance [ 38, 39, 41– 43] and activity [ 44– 48] data were obtained from multiple studies involving primary hepatocytes from human donors.
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For multifactorial diseases (diseases involving multiple genes), studies involving twins may be used to establish evidence for a role for genetic factors in a disease, while association studies may be used for the detection of susceptibility genes.
The nature of the Kelch domain and SAS1 sequence has been characterized by multiple mutational studies involving careful deletion or amino-acid substitution analysis [10] [13].
A limitation is that our benchmarking process was only tested in three multiple case studies involving three to four cases.
Multiple clinical studies involving many different surgical types have shown that preoperative rHuEPO is safe and effective.
Sunitinib has demonstrated potential for the treatment of breast cancer in multiple preclinical studies, involving the human breast cancer MX-1 xenograft model, where in combination with docetaxel, doxorubicin or fluorouracil it enhanced the antitumour activity of the chemotherapeutic agents and increased survival.
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