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Multiple studies have implicated rhomboid proteases in biologically and medically relevant processes.
Multiple studies have implicated damage to cardiac transverse (T -tubules as a key mediaT -tubulesitasion-contraction (E-C) coupling dysfunction and heart failure.
Though mechanisms of miRNA function remain obscure [51], [52], multiple studies have implicated the m7G cap structure as a cis-acting element that confers susceptibility to repression by miRNAs [53], [54], [55], [56].
Multiple studies have implicated rpoB mutations in the adaptation of E. coli to in vitro stress.
Multiple studies have implicated serotonin and the serotonin transporter (SERT) in the pathogenesis of PAH.
Multiple studies have implicated YY1 in the development and progression of cancer [ 51, 52].
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Multiple prior studies have implicated the patterning of focal adhesions in contact guidance.
Past studies have implicated multiple genes--on chromosomes 5, 6, and 11--in ADHD.
In vitro studies have implicated multiple domains of APP in neurite outgrowth including APP transmembrane isoforms, the secreted APP ectodomain, or CTFs and several mechanisms have been proposed [ 45, 49, 54, 55, 60, 61].
Activation of the TLR pathway increases the expression of various pro-inflammatory cytokines, like IL-6, IL-1 and TNF-α [ 36, 37].While earlier evidence has been obtained in the field of Alzheimer's disease (AD) [ 38, 39] and Multiple Sclerosis (MS) [ 40], recent studies have implicated TLRs also in the pathogenesis of PD [ 41– 41].
Recent studies have implicated the CHD4 ATPase in multiple stages of the DDR.
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CEO of Professional Science Editing for Scientists @ prosciediting.com