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However, it encounters multiple stresses in its underground burrows including darkness, energetics, hypoxia, hypercapnia, food scarcity, and pathogenicity.
Deb et al showed that M. tuberculosis can lose its acid-fastness under multiple stresses in vitro [23].
We found that when Mtb was subjected to the combination of multiple stresses in vitro, it developed higher degree of phenotypic resistance to Rif and INH indicating that a higher percentage of the mycobacterial population entered a dormant state.
BdMAPK cascade kinases were involved in the signaling pathways of multiple stresses in B. distachyon.
As one of important transcription factor family, the plant bZIP transcription factors play pivotal roles in developmental processes and multiple stresses in response to environmental tolerance.
A single bout of acute exercise induces multiple stresses in skeletal muscle, including increased demand for ATP and mechanical stress [ 6, 7].
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A few of the metabolic enzymes found to be expressed in response to multiple stresses represented in the ubiquitous category included S-adenosylmethionine decarboxylase, glyceraldehyde 3-phosphate dehydrogenase, methionine sulfoxide reductase, and copper amine oxidase [ 38, 73- 75].
Importantly, we have constructed a regulation network based on co-expression patterns of the expression profiles upon multiple stresses performed in this study.
RpoS binds to the promoter region of RNA polymerase, changing its specificity and activating translation of numerous genes that are important for cellular response to multiple stresses (reviewed in [ 8, 9]).
The blocking signal network we propose makes the effects of multiple stresses most predictable in the specific multiple stress environment.
Adiponectin is an insulin sensitising adipokine that protects beta cells against multiple stresses as found in our research and that of others [ 16– 16].
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