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In synthesis, autophagy is connected to multiple stress pathways.
This network model structure is critical to understanding complex stresses that can simultaneously activate multiple stress pathways.
This relative abundance of HSFs and HSPs under cold stress could suggest a mid-point involvement in cold stress response between multiple stress pathways similar to observations made by Swindell et al. [ 26] and indicate that HSFs could have other functional features apart from heat shock responses.
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Because DR induced the FIRE response to stress, we wondered if DR was a generally stressful condition that induced multiple stress response pathways.
The accumulated proline can function as an intracellular osmolyte (Chinnusamy et al. 2005), a scavenger for reactive oxygen species (ROS) (Matysik et al. 2002), a maintainer of cell structure (Verslues et al. 2006), and a signaling molecule that primes multiple stress response pathways (Maggio et al. 2002).
Our results suggest that TaSnRK2.8 may act as a regulatory factor involved in a multiple stress response pathways.
Equally interesting was the identification of module genes participating in multiple stress responsive pathways.
Heat shock factors represent interaction points connecting multiple stress response pathways.
CCGs are overrepresented among all of the classical plant hormone and multiple stress response pathways, as well as cell cycle and protein synthesis [ 70, 72].
Covington et al. investigated circadian microarray data, revealing that plant hormone and multiple stress response pathways are influenced by the circadian clock [ 34].
ER provides a platform where environmental signals can connect to biological structure and function, enabling the integration of multiple stress signaling pathways [ 9].
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