For some isoforms, multiple splice variants have been identified (indicated on the right-hand side).
This investigation showed that hCE expressed multiple splice variants of PMCA isoforms.
In particular, multiple splice variants are seen in the mouse brain [16].
The use of siRNA to dynamin1 and dynamin2 is problematic since they are expressed as multiple splice variants.
During FGFR expression, alternative splicing of FGFR transcripts produces multiple splice variants with different tissue-specific ligand specificities [13].
Approximately ∼10% of the gene descriptors in the array represent multiple splice variants that can also be deduced from the nucleotide sequences (Table S3).
From the 32 candidate genes chosen in activated T cells at 48 hours, we observed multiple splice variants for 17 candidate genes.
In agreement with the detection of multiple splice variants of mammalian (rodents and primates) prominin-1 [28] [31], we have amplified either corresponding or new variants in the three non-mammalian vertebrate models.
For several genes, the presence of alternative transcripts resulted in an uncorrected model (e.g. the model coding for the 247279 protein) indicating the method may not identify multiple splice variants when more than one variant is simultaneously present in dataset.
If multiple splice variants are identified, all will be reported.
However, this assay needs to be fully validated given the multiple splice variants.
