Sentence examples for multiple small molecule from inspiring English sources

Using straightforward chemistry, it is possible to covalently couple or display multiple small molecule initiators onto a protein surface.

The immense importance of SIRT1 in the process of anti-aging can be further ascertained from the implementation of multiple small molecule drugs which primarily act as SIRT1 activators (Hubbard and Sinclair, 2014).

This review surveys the most recent advances in the synthesis of different NIR-absorbing and emissive polymer nanoformulations, and their applications for cancer imaging, photothermal therapy, theranostics and combination therapy by delivering multiple small molecule chemotherapeutics.

Although the presence of RVG29 enhanced apparent brain delivery for multiple small molecule payloads, we observed minimal evidence for targeting to muscle or spinal cord, which are the known sites for rabies virus entry into the CNS, and enhancements in brain delivery were not prolonged due to an apparent aqueous instability of the RVG29 ligand.

This system is compatible with multiple small molecule deposition methods.

In parallel with the clinical development of bevacizumab, multiple small molecule inhibitors of the VEGF receptor tyrosine kinases have entered the clinic.

However, lack of sequence-specificity and the requirement of multiple small molecules necessitate the development of small molecules capable of mimicking the efficacy of their natural counterparts.

After a large-scale combinatorial screen of chemical libraries, Schimmer et al (2004a) discovered multiple small molecules with XIAP inhibitory activity, including the compound XAC 1396-11.

These efforts have led to the development of multiple small molecules with different chemical scaffolds that are highly selective for HDAC6 and allow for specific inhibition of HDAC6 at the cellular level.

In all cases, the multiple small molecules predicted to bind the predicted essential C. difficile proteins could be used to bias library selection for the rational development of new inhibitors.

In recent years, multiple small-molecule DPP-4 inhibitors have been reported [ 3, 4].