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Two months later, multiple skin biopsies were taken from all three pruritic cats and submitted to a histopathological laboratory (Patovet, Helsinki, Finland).
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Additionally, blood samples will be taken at multiple time points, and skin biopsies and swabs will be taken from selected patients on admission.
As skin biopsies contain multiple cell types, immunocytochemistry with anti-collagen I antibody was performed on a subset of the primary culture to confirm the type of the cells used in the study.
Microscopic examination of skin biopsies demonstrated multiple, narrow base, budding yeast cells the "steering wheels" of Paracoccidioides brasiliensis on Grocott's methenamine silver (GMS) staining.
It is therefore important to consider the possibility of complex infections in immunocompromised individuals and to look for multiple agents in skin biopsy specimens for such patients.
This clinical case emphasizes the necessity to consider the possibility of concomitant infections in immunocompromised individuals and the necessity to look for multiple agents in skin biopsy specimens for such patients.
We report that these protein biomarkers were similarly modified across two different mouse models of SMA, across multiple skeletal muscles, and also in skin biopsies.
Yet, high plasma lactate (3.5 to 4.4 mmol/l, normal below 2.2) prompted skeletal muscle, liver and skin biopsies that revealed a multiple respiratory chain enzyme deficiency in muscle and liver homogenate and cultured skin fibroblasts (Table 1) [42].
A.J.S. performed the skin biopsies.
Skin biopsies revealed epidermotropic infiltrates characteristic of CTCL.
In the presence of typical skin lesions, skin biopsies are an easy way to diagnose sarcoid.
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