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Control rats exhibited no congenital malformations of the brain and no appendicular or multiple skeletal deformities.
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Other associated features include multiple skeletal defects (chest and spine deformities), webbed/short neck, variable cognitive deficits, cryptorchidism, lymphatic dysplasia, bleeding diathesis, and, rarely, predisposition to certain hematologic malignancies during childhood.
Different types of OI exist, from mild to severe; they may lead to death, multiple bone fractures, skeletal deformity and short stature.
Congenital skeletal deformities 66-966%), with multiple skeletal 14-644%) and appendicular malformations 25-577%), were also induced by DMEP.
Children with rickets have weak bones and, often, skeletal deformities.
Peripheral neuropathy, skeletal deformities, high-arched feet, and rotation of the spine (scoliosis) also may occur.
Inherited deficiencies of blood lipoproteins also may result in peripheral neuropathy, retinal degeneration, and other motor and skeletal deformities.
The practice of orthopedics was pioneered in the ensuing decades by Jean André Venel, who established an institute in Switzerland for the treatment of crippled children's skeletal deformities.
Lack of vitamin D in children causes rickets, a disease characterized by inadequate mineralization of bone, growth retardation, and skeletal deformities such as bowed legs.
Three patients suffered from multiple skeletal injuries.
The total maxillary alveolar osteotomy (TMxAO) is not commonly used to manage maxillary skeletal deformities.
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CEO of Professional Science Editing for Scientists @ prosciediting.com