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Palladin exists in all vertebrates as multiple size variants generated from a single gene that possesses alternative promoters, i.e. a "nested gene".
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Size variants found in multiple miRNAs during Atlantic halibut development raise the question whether they play any regulatory role.
Multiple unit sizes: Offering multiple size options allows for more flexibility in terms of items being stored.
IsomiRs are size variants of miRNAs.
But, says Vucko, "multiple sizes are coming.
High quality sequence alignment revealed that the size variant alleles showing step-wise distribution contained the expected microsatellite repeat sequences with conserved primer binding sites, but corresponded exactly to the step-wise multiples of the number of repeat units.
Tapers exist in multiple sizes and angles.
Buy coils in multiple sizes.
Remarkably, whereas previous GWASs for other complex traits with far smaller sample sizes had discovered multiple novel variants, only one locus on chromosome 15, which harbors the cluster of nicotinic acetylcholine receptor genes CHRNA3-CHRNA5-CHRNB4, has been robustly associated with CPD across multiple GWAS of smoking [ 2- 7].
However, there is increasing evidence that the missing heritability in psoriasis could be explained by multiple genetic variants of low effect size from common genetic pathways.
However, there may be a middle ground in which multiple rare variants of moderate effect size play a key role in the etiology of some diseases.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com