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About 20 nociceptive ascending pathways have been uncovered so far, which terminate at multiple sites, from the upper spinal cord up to the thelencephalon.
Previous genetic and structural studies of MifM showed that the elongation arrest of MifM requires interactions between the MifM nascent chain and the ribosomal components at multiple sites, from the proximity of the peptidyl transferase center (PTC) to the central constriction of the polypeptide exit tunnel.
And in the weeks since Perfect Audience launched, it has also released a new feature — the ability to manage campaigns for multiple sites from a single account.
Among conserved poly(A) sites, 3711 were single sites and 1096 were multiple sites from 503 orthologous gene pairs.
In order to minimize variability arising from the exact location/size of the grafted tissue, we sampled multiple sites from slices that contained a visible transplant, as well as two to three additional slices anterior/posterior to the graft core.
These studies should include accurate and repeated HPV detection and genotyping of multiple sites from parents, siblings and care givers as well as assays to distinguish between markers of inert HPV DNA detection and markers of active HPV infection.
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On a related note, game trailers have been pulled from multiple sites for not complying with ESRB guidelines.
The only way to address these complex issues will be to directly compare transcriptomes and proteomes in matched primary tumors and metastases (preferably from multiple sites) microdissected from adjacent normal tissues.
Combining indicator information from populations at multiple sites, and from multiple species, can assist in reducing single-site effects, and potentially make indicators based on seabird breeding performance more robust [108].
Besides site-specific deadenylation of the A4324 in the Sarcin/Ricin domain of rat ribosome, this protein could also release the adenine base from DNA molecules at multiple sites and from AMP, ADP, dAMP and adenosine.
These observations indicate that ORC interacts with Rbf1 through multiple sites distinct from the dE2F binding site.
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