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Using a head-restrained preparation allows recordings of well-isolated single units at multiple sites during repeated experimental sessions.
We used a natural experiment in the shortgrass steppe of northeastern Colorado, USA, where prairie dogs were extirpated from multiple sites during an outbreak of epizootic plague.
Mycetomic rickettsiae in booklice migrate to multiple sites during the developmental stages of booklice through several tissues e.g. fat body, midgut, ovaries, and finally form a pair of mycetomes located between the midgut and ovaries in the adult stage [6].
Most clinical trials in SLE slowly accrue fewer than 10 patients from multiple sites during a year.
Given that A. maculatum ticks were collected at multiple sites during multiple years, and that these ticks have recently been collected in large numbers, this species is probably established in west-central Kentucky and northern Tennessee.
We measured temperature at multiple sites during experimental induction and reversal of hypothermia in swine with a novel esophageal cooling device, hypothesizing that agreement between sites would fall within standard acceptance criteria (average difference ± 1.96 standard deviation of the difference) in Bland-Altman analyses.
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With multiple sites, the strain during the correction is shared [18].
In xMELK, we have identified multiple sites phosphorylated specifically during mitosis (Badouel et al., 2006).
We utilise their framework to describe the experience of recruiting a large cancer cohort from multiple sites across Great Britain during 2011/2012.
SopB has a relatively long half-life and thus it could easily have multiple sites of activity during the infectious process, and which may play an important part in allowing Salmonella to successfully transition from its invasion to intracellular phase.
Biopsy of multiple sites or serial biopsies during treatment could address some of these issues, however it may not be feasible due to the invasiveness of the procedure and the potential risks to the patient.
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