Exact(1)
These determinants include the average (or 'main') effects of each possible nucleotide at the variable RE sites, as well as epistatic interactions, which occur when a combination of nucleotides at multiple sites affects affinity differently from expectation based on each nucleotide's average contribution.
Similar(57)
Of patients with ecthyma gangrenosum (figure 1B), 10 had multiple sites affected.
Synchronous metastases are present in up to 30% of patients, with multiple sites affected in 95%[2,3]].
In cases where multiple TF molecules do interact, it is generally unknown how the spatial organization of their binding sites affects DNA binding.
"This site affects multiple lives.
Failure of A-to-I conversion at this site affects multiple AMPA receptor properties, including the Ca2+ permeability of the receptor-coupled ion channel.
This result led us conclude, that the tau isoforms are preferentially mono-ubiquitinated at multiple sites by axotrophin affecting at least four lysine residues in four-repeat tau isoforms (0N4R, 2N4R) and two lysine residues in three-repeat 2N3R isoform.
Most pain in patients aged ≥50 years affects multiple sites and yet the predominant mode of presentation is single-site syndromes.
As a project manager, my role as a team member of projects that affect multiple sites and functions of my company's Operations division affords me the opportunity to work on initiatives that are critical to our bottom line.
They commonly affect multiple sites within the abdomen including bowel, lymph nodes and solid organs.
Positively charged silver ions are highly reactive and affect multiple sites within bacterial cells.
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