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Prior to interpretation, for pairs of polymorphisms where there were multiple significant interactions (e.g., additive-additive and dominant-recessive), we selected the model that provided the most parsimonious fit to the data using Akaike's information criterion (AIC) from the covariate-adjusted model.
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In line with our hypothesis, we identified multiple significant genetic interactions associated with cingulate amyloid deposition.
The false discovery rate method controlled for multiple analyses.No significant interactions comparing active versus sham stimulation over time were evident.
In addition, after adjusting for multiple testing, no significant interactions between any pairs of SNPs on incident T2DM were observed (data not shown).
Second, after conducting Bonferroni correction for multiple comparisons, no significant interactions between lifestyle factors and TP53 rSNP78486 SNP remained; therefore we cannot exclude the possibility of spurious associations due to multiple comparisons.
This is to be contrasted with the multiple Bonferroni-significant interactions found in regular data (see section 4.2).
Coordinated control of multiple competing objectives with significant interactions, together with many shared uses of actuators to control multiple variables, implies that highly integrated control logic and shared actuator management will be required.
A wide variety of explanatory variables displayed significant interactions with multiple sentencing outcomes, from a high of n = 17 antecedents positively influencing the probability of being sentenced to jail, to a low of n = 2 antecedents for being ordered to submit to random drug testing.
In summary, QTL interactions are identified by finding significant interactions between multiple GMs using GMNs.
After accounting for multiple testing, there were no significant interactions for mammographic density between the investigated SNPs and current use of MHT.
By multiple logistic regression there were no significant interactions between variables.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com