Despite data showing activation of multiple signalling pathways upon RAGE ligation, only little is known about proximal signalling events directly downstream of the receptor [ 11, 12].
Like other well-characterised pharmacological therapies, Fenretinide has been shown to affect multiple signalling pathways.
Cancer is quite complicated as it involves multiple signalling pathways and it may be caused by genetic disorders.
Increasing evidence has suggested that miRs are translational repressor components of multiple signalling pathways.
It is clear that the phenotypic effects of defective sterol profiles affect multiple signalling pathways that impinge on each other.
mTOR is an evolutionarily conserved serine/threonine protein kinase which integrates multiple signalling pathways regulating gene expression involved in metabolism, cell survival, and cell proliferation [15].
The control of tissue growth in Drosophila requires the action of multiple signalling pathways that often have conserved roles in mammalian development and cancer [1], [2], [3].
Although multiple signalling pathways may be involved, STAT6 critically regulates the differentiation and cytokine production of Th2 cells and the expression of eotaxins.
Selenite has been reported to activate multiple signalling pathways.
Multiple signalling pathways contribute to tumour growth and development.
Multiple signalling pathways are suggested to be involved.
