Sentence examples for multiple signalling networks from inspiring English sources

During dental lamina formation, the thickened epithelium invaginates into the adjacent mesenchyme and this involves multiple signalling networks.

A general coregulator such as Gro/TLE makes a perfect integrator of inputs from RTK signal transduction cascades with multiple signalling networks.

GO-STRING analysis revealed multiple signalling networks activated by doxorubicin and etoposide and supports the complexity of the cellular response to Top2 poisons.

The contribution of multiple signalling networks to tumorigenesis also accounts for the limited responses seen with MEK inhibitors alone.

The evidence so far indicates that OPN functions as a nodal point in multiple signalling networks that lead to malignant transformation.

Thus, they play a key role in integrating multiple signalling networks, which together ultimately govern cell survival, proliferation and migration [ 1].

Multiple signaling networks and feedback loops "downstream" of KRAS have been described that respond to obesogenic diets.

Although two VEGF receptors are known, VEGF-R1/flt-1 and VEGFR-2/KDR/flk-1, VEGF was shown to signal mainly through VEGFR-2, which upon ligand binding becomes tyrosine phosphorylated and activates multiple signaling networks [3].

These changes collectively demonstrate that the regulation of multiple signaling networks is corrupted in CD22ΔE12-Tg CD22ΔE12-Tg

The ultimate cellular response reflects the input of multiple signaling networks and does not result from a key "molecular target" or dedicated signaling pathway.

Second, they imply that combined inhibition of multiple signaling networks in human cancer cells might be required in order to meaningfully alter their natural progression.