Sentence examples for multiple signalling cascades from inspiring English sources

CD40 signalling results in the activation of multiple signalling cascades including signal transducers and activators of transcription factor 3 (STAT3)(Hanissian & Geha, 1997).

Multiple signalling cascades such as (1) the phosphoinositide-3 kinase (PI3K -AKT, (2) Ras-Raf- extracellular signal-regulated kinase (ERK) mitogen-activated PI3K -AKTinase (MAPK), and (3) signal transducer and activator of transcription (STAT) pathways are activated by the assembly of these signalling complexes.

Overall, adipogenesis is an ordered process, involving multiple signalling cascades which are further discussed later in the present review.

The question of how IL6 integrates multiple signalling cascades to coordinate nutrient homeostasis in mammals remains unanswered.

This signalling route is distinct from the better-characterized, traditional EGFR pathway that involves transduction of mitogenic signals through activation of multiple signalling cascades.

However, injected CagA also interacts with many other host cell proteins, involved in multiple signalling cascades, which are discussed elsewhere [ 7, 8].

Stimulation of the T cell receptor (TCR) complex initiates multiple signaling cascades that lead to the activation of several transcription factors, including the NF-κB family members.

BAP1 is subjected to multiple signaling cascades that impart several post-translational modifications on this DUB including phosphorylation and ubiquitination, both of which coordinate BAP1 function9,13.

Alone or in combination, these REs control COX-2 expression through multiple signaling cascades, making it an important component in the response to inflammatory and cytotoxic stress.

Obesity-induced cardiomyopathy may be mediated by alterations in multiple signaling cascades involved in glucose and lipid metabolism.

These signals activate and suppress multiple signaling cascades regulating bone formation and resorption.