Sentence examples for multiple signaling roles from inspiring English sources

For the muscarinic M2 receptor, allosteric, orthosteric and dualsteric binding small molecules are available, which helps to elucidate multiple signaling roles [2 4].

The sphingosine – S1P rheostat plays multiple signaling roles in higher animals [reviewed in [ 38]].

Ceramide is a bioactive lipid; it has multiple signaling roles in endothelial cells, macrophages, and fibroblasts [ 73].

The TRAF2 and TRAF5 proteins are known to play multiple signaling roles in the IL-17R and TNF receptor signaling pathways [ 51].

Moreover, TRAF3IP2 interacts with other TRAF proteins such as TRAF3 and TRAF6 that play multiple signaling roles in the IL-17 and TNF- α signaling pathways [ 8, 22, 25, 26].

Structural proteins that are bound by integrin receptors – collage, laminin and fibronectin subunits – are largely encoded by bimodal genes, confirming the fact that the multiple signaling roles of integrins are coupled with the extracellular environment [ 43].

Through computational modeling and experimental evaluation, we explore the signaling roles of distinct NF-κB dynamics that occur in multiple timescales.

These results add to a growing body of evidence that Lrig proteins exert their effects through multiple signaling pathways with diverse roles in development and disease.

Given the important role of Jak2 in cell signaling, we anticipate that Jak2 deficiency would affect the activation of multiple signaling pathways of DCs.

DNA damage activates multiple signaling cascades.

Ki-67 is a marker of proliferation, being detectable in all stages of the cell cycle, except G0. 14-3-3 14-3-3 14-3-3daptor protein which isigmaolved is multiple signaning padaptor, having a role in inhibiting G2/M cell cycle proteinsion under p53 regulation.