Sentence examples for multiple signaling proteins from inspiring English sources
Active anticancer components are known to exhibit a consistent antitumor effect by blocking abnormal expression alterations of multiple signaling proteins, such as VEGF, p53, JAK-STAT, and CDC14A [454 55] 55].
TRAF6 belongs to E3 ubiquitin ligase family which induces the activation of multiple signaling proteins including Akt through formation of Lysine-63-linked poly-ubiquitin chains [76].
We therefore tested whether any of multiple signaling proteins, mainly kinases, were activated using a specific, semi-quantitative method to identify them with Kinetworks™ screens.
Application of external mechanical force enhances integrin clustering and the subsequent recruitment of focal contact proteins, that, in turn, associate with the actin cytoskeleton and activate multiple signaling proteins including focal adhesion kinase (FAK), Src family kinases, Rho GTPase, and integrin-linked kinase (ILK), to promote cell growth, migration, and differentiation [23], [24].
In addition to Smad pathway, multiple signaling proteins have been implicated in the TGF-β-induced EMT.
Protein oligomerization mediated by the death domain (DD) superfamily, which include CARDs, has been studied in multiple signaling proteins.
Paxillin is a multi-domain adapter molecule which is important for recruiting multiple signaling protein to a specific location within the cell [ 42].
For quantitative measurement of single-cell proteins, a microfluidic image cytometry was reported for proteomic analysis of multiple oncogenic signaling proteins of clinical brain tumor specimens [ 73].
They can regulate multiple intracellular signaling proteins involved in cell proliferation and differentiation and have important roles in mitogenic and antiapoptotic function of nicotine [ 49, 50].
In this study, 20% of proteins that were upregulated upon tumor onset were considered likely to be associated with a tumor-specific host response, including multiple macrophage signaling proteins, TAM-related proteases, and ECM proteins [ 83].
There may be multiple pathways and signaling proteins other than IRS-1 involved in this interaction between T and insulin.
