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Cbl proteins interact with multiple signaling molecules including Lck, Vav, TCR-ζ, PLC- γ1, and Grb2[5], [7].
Cbl inactivation, which rescues the developmental defect in Vav1-/ thymocytes, thus enhanced activities of multiple signaling molecules, including the early TCR-mediated signal molecule Lck, in addition to enhancing normally Vav1-dependent downstream events.
Caveolae and lipid rafts are cholesterol- and sphingolipid-rich plasma membrane microdomains, in which multiple signaling molecules and receptors are assembled to provide the molecular proximity for rapid, efficient, and specific activation of downstream signaling [18].
Our studies together with previous reports [36], [37] indicating that PTK6 may regulate multiple signaling molecules infer that there may be multiple mechanisms by which PTK6 regulates cell growth and survival.
The mechanisms of regeneration are complex and involve multiple signaling molecules, transcriptional factors, and genes.
Multiple signaling molecules are located at the cell-cell contact sites in direct proximity to the AJ complexes.
Similar(38)
Osteoclastogenesis involves complex pathways with intricate relationships between multiple signalling molecules.
These regulators are activated or repressed by the integration of multiple signalling molecules in spatio-temporal gradients.
Caveolin is the major structural component of caveolae, plasmalemmal organelles which function as macromolecular vesicular transporters and organizers of multiple signalling molecules [10].
So there may be multiple signal molecules involved.
In Drosophila, PCP is a complex process involving the spatial organisation of multiple signalling molecules (Jones and Chen, 2007).
More suggestions(14)
numerous signaling molecules
multiple signaling partners
multiple signaling networks
multiple signaling roles
multiple signaling cascades
multiple signaling processes
multiple signalling molecules
multiple ubiquitin molecules
multiple signaling mechanisms
multiple protein molecules
multiple signaling proteins
multiple effector molecules
multiple signaling systems
multiple target molecules
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