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A key design consideration in developing contrast agents is obtaining distinct, multiple signal changes in diseased tissue.
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The following findings were considered to be pathological: myelitis, brain atrophy leading to expansion of the ventricles, multiple high signal changes in the white matter, multiple sclerosis-like changes and infarctions.
[35] Therefore, the stimuli-triggered disassembly of Au NCs can be used to visualize a neoplastic site with high resolution by multiple optical signal changes: the loss of scattering signal and an increase in Doppler variance frequency spectrum [36, 40].
This study's hypothesis of obtaining multiple, stimuli-responsive optical signal changes using molecularly engineered inorganic NPs can further be expanded to drug delivery and other imaging applications.
These results indicate that HYF127c/Cu induces changes of multiple signal pathways in cancer cells.
Significant overall signal changes (corrected for multiple tests, Table 1) were also observed during ipsilateral presses.
The multiple signal transduction systems for sensing dynamic changes in carbon source and temperature, and the type IV pili, which are likely to be useful for clinging to the chimney, allow D. desulfuricans to survive in such a harsh environment.
Bacteria utilize two component systems to sense changes in the environment by multiple signal components including heavy metals and control gene expression in response to changes in signal molecules.
Multiple Signal Classification.
Its expression seems to be regulated by multiple signaling pathways, microenvironmental parameters, changes in substrate concentration and pH[ 8].
Our work in combination with the study of Box et al. [ 27] adds further insight into the essential role of ELF3 in integrating multiple signals to promote architectural changes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com