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Our implementation, as described in Maddison et al. [ 1] uses several techniques to overcome the limitations of the Brent [ 24] optimizer, including using multiple searches from randomly generated starting points, and the option of starting searches from values estimated from more constrained models.
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One could easily recommend reducing this small risk of overestimating support by representing each bootstrap replicate by a consensus tree derived from multiple searches, but this probably suffers from a too high cost-benefit ratio to be practical in most analyses: 10 ratchet iterations require roughly a 20-fold search time compared to a simple search.
The first type combines ranking from single searches based on multiple similarity measures, while the second one combines ranking from multiple searches based on a single similarity measure.
This assumption is that the availability of information resulting from multiple searches will increase the likelihood of detecting active molecules when compared to the use of just a single search.
Once the results from multiple searches will be merged by the librarian (DZ) using the reference management software EndNote, duplicate records will be removed (DZ and TH).
They've also conducted multiple searches.
Multiple searches were conducted.
Do multiple searches.
To reduce the computation cost and fast the search process for real-time application, we apply multiple global searches from coarse scale to fine scale by gradually decreasing the search step size and narrowing the search area.
To be more efficient, we leverage search and make use of voting from multiple search result lists to rank the best matched URL at the top.
Metasearch engines like Dogpile, Ixquick and Vivisimo combine the votes from multiple search engines Google and others into a collective ranking.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com