A 32-year-old female with multiple sclerosis presented with thigh pain and weakness in the left lower extremity for 3 months.
A 34-year-old Caucasian female with multiple sclerosis presented with 1 week of blurry vision in both eyes during treatment with natalizumab.
About 20% of patients with multiple sclerosis present with optic neuritis (Costello, 2013).
In majority of patients, multiple sclerosis initially presents as a relapsing remitting disease with acute inflammatory attacks against CNS tissue, followed by complete recovery.
About 10 15% of patients with multiple sclerosis (MS) present with gradually increasing neurological disability, a disorder known as primary-progressive multiple sclerosis (PPMS).
Open image in new window Fig. 11 A 30-year-old female patient affected by relapsing-remitting multiple sclerosis (MS) presenting with a large demyelinating plaque in the right centrum semiovale.
An example is multiple sclerosis, which can present with nothing more than transient blurred vision and may take years before other, more specific symptoms appear.
Beyond evidence for the mechanisms of pathogenesis in multiple sclerosis, the findings presented here have a more direct diagnostic potential.
Analyses to test for potential association(s) between these SNPs and multiple sclerosis will be presented elsewhere.
With the wider availability of 7-T magnets interest has increased in the clinical application of ultra-high field MRI, and recently 7-T imaging results of a multiple sclerosis patient were presented, including a FLAIR image [ 11].
