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Setting Specialist multiple sclerosis clinics in 70 centres in the United Kingdom.
Participants were 18 right-handed patients (15 female, 3 male) with clinically definite multiple sclerosis (McDonald et al., 2001) recruited from local multiple sclerosis clinics and the North Jersey chapter of the National Multiple Sclerosis Society.
Briefly for this study, between August 1993 and January 2008, multiple sclerosis clinics across Canada, with appropriate consent, used standardized telephone interviews to screen individuals with multiple sclerosis and to collect data about themselves and their families, including age of onset.
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To investigate whether electronic continence questionnaires aid early identification and optimizes management of sphincter dysfunction in a multiple sclerosis clinic.
Patients were identified through the Rennes Multiple Sclerosis Clinic, which is a regional referral centre for multiple sclerosis in West France (Leray et al., 2007).
Similarly, the multiple sclerosis patients were being treated at a multiple sclerosis clinic, and many may not have been severely impaired at the time they were interviewed.
The London Multiple Sclerosis Clinic (London Health Sciences Centre, Canada), established in 1972, provides long-term care for patients with multiple sclerosis from its referral area of south-western Ontario.
It is likely that our cohort missed some patients with very severe disease who died before attending our multiple sclerosis clinic.
The decision of initiating first line disease-modifying treatment (Interferon beta 1a in all cases) was made by an experienced multiple sclerosis neurologist at the multiple sclerosis clinic at Glostrup Hospital and was not influenced by the study in any way.
Patients referred to Rennes Multiple Sclerosis Clinic mainly live in Brittany (60%), Pays de Loire (20%) or bordering regions (14%), the remainder coming from other French or European regions (6%).
During the first academic year, all PCMH continuity sites were within Family Medicine practices; however, during subsequent years, sites included internal medicine (HIV and heart failure clinics; Veterans Affairs location), neurology (multiple sclerosis clinic), psychiatry (mood disorder clinic), and pediatrics (adolescent eating disorders clinic).
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