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Whether these sublineages reflect multiple samplings from a limited number of outbreaks, or if they reflect cross-boundary introductions is not clear.
In three cases with multiple samplings from both the primary and recurrent surgery some mutations (NRAS Q61R, BRAF V600E, SMAD4 R361G) were stable across all samples, while others (KRAS G12V, BRAF G469V) were unstable.
Multiple samplings from both the primary and recurrent setting from three cases (LGSC-9, LGSC-10 and LGSC-12) were used to assess the spatial and temporal stability of features (see Figure 2C-E for overview of clinical course).
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Thus, our data are a reflection of one representative strain from all individuals involved in the current study, unless multiple samplings identified different strains from the same individual.
For some combinations of antibiotics and sampling times, multiple samples from evolved biofilms showed higher variability than seen among multiple samples from the ancestral clone.
Two studies could not be used in pooled analyses: one presented means of GFAP levels from multiple samplings over time (GMR 1.98 (95% CI 1.06 to 3.70)) while the other presented the highest peak levels of GFAP during the acute phase of care (GMR 3.20 (95% CI 1.82 to 5.65)).
The sensitivity of qRT-PCR for measuring mRNA levels, however, would require only small amounts of tissue that could be obtained from a needle biopsy, thereby facilitating multiple samplings.
We have reanalyzed data from a previous cohort of women with multiple samplings to determine whether the trajectory of increase of placental corticotropin-releasing hormone provided more information than did a single sample.
For example, tap water sampled from room 11 had a distinct genotype from that sampled from shower water in the same room and this was consistently found over multiple samplings.
Mr. Shepard's soupy rendition of pasta e fagioli ($8) was a success on multiple samplings.
Baclofen elimination half-lives were calculated in patients with multiple samplings.
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