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Two previous studies have used multiple sampling within individuals to provide a statistical basis for detecting transcript variation between genetically identical mice.
Multiple sampling within individuals is not necessary in an experiment aimed at making between-group comparisons, but it is essential if the aim is to identify significant variation between individuals within the same experimental treatment group.
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Neyman and Pearson were solving problems surrounding rates of defective materials and rejection of lots where there were multiple samples within each lot – a situation which clearly does require a p-value adjustment.
We analysed understory regeneration density and distribution in relation to canopy gap size and condition on multiple sample areas within a 360 km2 area of old-growth balsam fir (Abies balsamea [L.] Miller) forest on Anticosti Island, Canada.
First, we have allowed for the inclusion of multiple sampled lineages within each species.
We similarly did not find any temporal variation of the MELAS mutant load in multiple samples taken within 10 to 39 GW (Tables 4A and B).
Together GC MS and H-MCR constitute a reproducible platform that allows for generation of global metabolomics for multiple sample comparisons within and between sample batches (Jonsson et al. 2006; Thysell et al. 2012).
The results of our current analysis do agree with these studies about the added value of multiple FIT sampling within a given screening schedule.
In this study, we collected multiple samples of tissues within each of several genetically identical mice.
We isolated multiple samples from regions within an individual patient's lung varying by degree of emphysema and by location (for example, apical, basal), and used Lm to quantify the degree of emphysema severity within each sample.
In free-ranging animals multiple samples were taken within several hours when degradation products had not yet been produced, while samples from porpoises in rehabilitation were taken over a period of several days.
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