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This broad range of defined HIV-1 genotypes suggested the multiple route of transmission for the import of new HIV-1 genotypes into the Hong Kong local population.
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For further information on diseases with multiple routes of infection, see [10, 11].
NoVs have multiple routes of transmission including faecal oral, aerosolized vomitus, person to person and via contaminated surfaces or food and water.
High CYP mediated clearance as well as glucuronidation were targeted to achieve high intrinsic clearance coupled with multiple routes of clearance to minimise drug-drug interactions.
Due to short lived immunity, high viral diversity and multiple routes of transmission, norovirus epidemiology is complex.
Targeted antiretroviral PrEP could be particularly effective at slowing the spread of HIV-1 if a single antiretroviral combination were found to be broadly protective across multiple routes of transmission.
Innovative vaccine platforms composed of adaptable adjuvants able to appropriately modulate immune responses, induce long-lived immunity in a single dose, and deliver immunogens in a safe and stable manner via multiple routes of administration are needed.
We performed comprehensive efficacy studies to determine whether a single antiretroviral PrEP approach can protect from multiple routes of HIV transmission using a uniform and highly relevant experimental platform.
These vectors were initially chosen based on reports of improved cellular immunogenicity when used in a prime-boost combination in humans with a variety of antigens [7] [9] and on their ability to control viremia after multiple routes of SHIV challenge in rhesus macaques [10], [11].
THEA has therefore shown multiple routes of exposure and uptake.
Develop improved methods for assessing exposures to multiple environmental chemicals and multiple routes of exposure.
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