Sentence examples for multiple role in from inspiring English sources

One of the proteins orchestrating DNA damage response is ATM (ataxia telangiectasia mutated), which plays a central and multiple role in the cellular stress response by monitoring and maintaining DNA integrity (reviewed by [ 4]).

Among tumour progression biomarkers, already known for their involvement in other neoplasia, a crucial role is ascribed to the urokinase-type plasminogen activator receptor (uPAR), which plays a multiple role in extracellular proteolysis, cell migration and tissue remodelling not only as a receptor for the zymogen pro-uPA but also as a component for cell adhesion and as a chemoattractant.

In conclusion PI3K has multiple role in cytokine receptors trafficking and signaling: promoting its endocytosis by regulating the Rac1-mediated actin cytoskeleton reorganization at the plasma membrane, transducing the proliferative signal and controlling the signal by ensuring a negative feedback loop increasing IL-2R uptake and its degradation.

These hubs, in turn, play multiple roles in the economic life of a metropolitan area.

The UN Framework Convention on Climate Change has multiple roles in the adaptation arena.

Here are the five best, and five worst, actors who've taken multiple roles in the same film.

For some critics, the company's multiple roles in the world of painkillers is troubling.

Anita Gillette ("Chapter Two") and Jamie Farr (Klinger in "M*A*S*H") play multiple roles in these one-acts about a South Florida apartment complex (2 00).

Two weekends ago, over three days, he performed multiple roles in the school's production of "Phantom," a musical based on "Phantom of the Opera".

4. Jean-Claude Van Damme (The Order, 2001) By 2001, Jean-Claude Van Damme had played multiple roles in Double Impact, Timecop, Maximum Risk and Replicant, each to slightly diminishing effect.

Livestock extension officers have multiple roles in the study area.