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Finally, the central plain of Thailand is an area with intense farming activities, including pig husbandry, reflecting strongly the convergence across multiple risk models here.
Multiple risk models that incorporate routinely collected data (e.g., sex, age, body mass index, parental history of T2D, drug treatment, and smoking status) have already been shown to predict the risk of developing T2D reasonably well [ 17, 18].
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We identified multiple predator effects on prey by comparing observed predation rate to that predicted from the multiple risk model.
This coheres with multiple risk factor models of aggression and the ecological model of child development, which integrates individual, family and environmental factors [ 4, 29].
Previous studies identified various patient characteristics related to final outcome in patients with severe sepsis, and multiple risk prediction models have been developed to adequately risk stratify patients based on combinations of these characteristics [7].
To be sure, there are, in fact, multiple risk factor models: Framingham, SCORE, QRisk and Reynolds.
The paradigm shift that occurred as researchers and practitioners moved from a single agent model of causality to a multiple risk factor model in which independent causes may work synergistically to contribute to disease states is beyond the scope of this paper.
The multivariate model selection was performed by a stepwise strategy using the likelihood ratio test to create a multiple risk factor model.
Kaplan Meier survival analysis, log-rank statistics, and Cox regression analysis were employed to identify risk factors and to create a multiple risk factor model.
To build a multiple risk factor model, we used multivariate Cox regression containing all predictors as candidate variables, since factors that are not univariately significant may nevertheless become significant when included together in the model.
To address this conceptual limitation, investigators developed multiple risk-assessment models that refine those criteria [ 61, 63, 64].
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