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In the next month's issue of Science, more than 100 biologists signed multiple response letters in defence of collecting.
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Some sentences from complete response letters contained multiple statements.
Conclusions FDA generally issued complete response letters to sponsors for multiple substantive reasons, most commonly related to safety and/or efficacy deficiencies.
We have shown that the FDA issues complete response letters to sponsors for multiple substantive reasons, most commonly related to safety and efficacy.
Most studies measured multiple response variables.
†Includes 11 complete response letters without associated press releases.
NB: Multiple response options.
Multiple response question.
On the cover letter/post card at each mailing, non-responding GPs were invited to provide via post a reason for non-response (multiple response options provided and included 'other') and minimum data about themselves (gender, year of qualification, practice size and setting) in order to permit assessment of non-response bias [ 10].
We identified 687 statements in all 61 complete response letters (median eight statements per letter; range 1-38).
Thirty seven press releases (61% of complete response letters) included one or more statements matching letter statements (fig 1).
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