Sentence examples for multiple respiratory chain from inspiring English sources

To determine the actual incidence of mitochondrial DNA (mtDNA) depletion syndrome in multiple respiratory chain deficiency.

The mtDNA depletion resulted in reduced steady state levels of mtDNA encoded proteins and multiple respiratory chain deficiencies.

Downregulation of the C12orf65 protein results in a mitochondrial translation defect and profound multiple respiratory chain defects.

Finally we discuss the possible mechanisms by which multiple respiratory chain complex defects may occur in these cells.

Most of these gene defects result in histological (COX-deficient or ragged red fibres) and biochemical abnormalities (multiple respiratory chain defects) in affected organs.

Multiple respiratory chain deficiency was found in muscle and fibroblasts of the subject as well as abnormal assembly of complexes I and IV.

We report three families presenting with hypertrophic cardiomyopathy, lactic acidosis, and multiple defects of mitochondrial respiratory chain (MRC) activities.

Furthermore, we have shown that multiple complexes of the respiratory chain are involved in more than 50% of deficient crypts.

tko 25t manifests multiple deficiencies of the respiratory chain and OXPHOS, and exhibits an impaired response to sound and defective male courtship (Toivonen et al., 2001).

We have also demonstrated for the first time that multiple complexes of the respiratory chain are affected simultaneously and that the COX/SDH histochemical assay is an extremely effective method to identify cells which are respiratory chain deficient and contain mtDNA mutations.

Patients carrying Twinkle mutations develop multiple deletions of mtDNA, deficient respiratory chain function and neuromuscular symptoms.