Sentence examples for multiple resistance mutations from inspiring English sources

We report the case of a multi-experienced patient, infected with an HIV-1 strain, with selected multiple resistance mutations.

All patients included in this study exhibited multiple resistance mutations at baseline with a median number of mutations of 7 and 3 for RT and PR, respectively.

The majority achieved virologic suppression despite multiple resistance mutations.

Clinical isolates often possess multiple resistance mutations, but the exact number varies between different antimicrobials.

"The probability of multiple resistance mutations occurring in a single organism is equal to the product of their individual probabilities.

When planning salvage regimens for children failing on NRTI/NNRTI-based HAART; pediatricians are often faced with multiple resistance mutations and limited options.

In the first scenario, virus titers are suppressed by antiviral drugs, and the use of multiple drug therapies ensures that viruses need to simultaneously acquire multiple drug resistance mutations.

Unfortunately, the emergence of HIV variants with multiple resistance gene mutations resulted in a high HIV load and low CD4+ T cell count.

In the case of a fitness cost of resistance, the sequential acquisition of multiple deleterious resistance mutations should result in a cumulative fitness deficit that may reduce the likelihood that a strain will evolve extensive drug resistance.

AT = anti-tuberculosis, MDR = multiple drug resistance Mutations in the catalyst region of the rpoB gene are associated with the development of resistance to rifampicin.

In turn, this raises fundamental questions regarding the ability of Mtb to harbour multiple drug resistance mutations while retaining the ability to infect, persist, and cause disease in its obligate human host.