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Other species are intrinsically susceptible but can acquire AME-encoding genes on plasmids that often carry multiple resistance determinants, including ESBL [80].
Since these plasmids commonly bear multiple resistance determinants, a single plasmid conjugation may suffice to confer a multidrug resistance phenotype to the recipient strain. .
Since these plasmids commonly bear multiple resistance determinants, a single plasmid conjugation may suffice to confer a multidrug resistance phenotype to the recipient strain.
Other species are intrinsically susceptible but can acquire AME-encoding genes on plasmids that often carry multiple resistance determinants, including ESBL [ 80].
These MDR strains co-carrying diverse and numerous multiple resistance determinants may impose limitations in the therapeutic options available for the treatment of infections.
This is concerning because it has previously been reported that the gene for high-level mupirocin resistance can be found on conjugative plasmids that carry multiple resistance determinants for other antimicrobial agents [ 21].
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The expression of tetracycline resistance genes was determined in all S. suis strains possessing multiple tetracycline resistance determinants according to techniques described previously with modification [ 17].
Additional evidence supporting the idea of horizontal transfer of multiple antimicrobial resistance determinants comes from a recent study conducted on multidrug resistant S. Agona isolates containing a DT104-like antimicrobial resistance gene cluster in their genome (28 ).
They were first detected on plasmids bearing single and multiple drug resistance determinants in human pathogens, and it is abundantly clear that integrons have played a major role in the evolution of this public health menace.
They are frequently associated with integrons (genetic dissemination systems) containing multiple antibiotic resistance determinants that are easily transferred among species.
From January 2010 to December 2010, non-duplicate KPC-KP isolates from our hospital were screened for rmtB and multiple other resistance determinants with PCR.
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multiple resistance phenotypes
multiple resistance mechanisms
multiple interacting determinants
multiple cognitive determinants
multiple sequence determinants
multiple behavioral determinants
multiple resistance mutations
multiple health determinants
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multiple resistance integrons
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multiple biofilm determinants
multiple physiologic determinants
multiple resistance traits
multiple resistance factors
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