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Single or multiple relapses after initial treatment are common and bring about more severe symptoms.
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MCL is resistant to conventional chemotherapeutic regimens with a tendency for multiple relapses.
Multiple relapses are common.
These patients are susceptible to multiple relapses.
Prior to the development of novel biologically based therapies for multiple myeloma, relapses after successive treatment regimens resulted in progressively shorter response durations [ 1], which in part reflected the occurrence of drug resistance.
Multiple myeloma relapsing after allogeneic stem cell transplantation (alloSCT) has a poor outcome.
However, when secondary progressive multiple sclerosis was excluded, the relapses after DSS 3 might still have some influence on disability, although the comparison did not reach statistical significance due to the small numbers of patients.
There is no standard therapy for multiple myeloma (MM) relapsing after an autotransplant.
Hence, enhancing remyelination efficiency, both in terms of extent and quality, may not only restore function after multiple sclerosis relapses but also aid neuroprotection, avoid neurodegeneration and slow or prevent progressive disability.
In contrast, relapses after DSS 3 did not have a similar influence on disability progression in the large majority of patients with multiple sclerosis.
Relapses after 20 months have been rare.
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CEO of Professional Science Editing for Scientists @ prosciediting.com