Follicular lymphoma (FL) is characterized by multiple relapses and progressively shorter response durations with subsequent therapies.
Despite of advances in pharmacological and non-pharmacological treatments, bipolar disorder often entails multiple relapses and impaired psychological functioning.
Disease courses are typically characterized by multiple relapses and progressively shorter response duration with subsequent lines of therapy.
Despite substantial advances in pharmacological and nonpharmacological treatment possibilities, bipolar disorder often entails multiple relapses and impaired psychological functioning (Berk et al. [2010]; Solomon et al. [2010]).
Mepolizumab may be useful for EGPA patients who experience multiple relapses and cannot stop glucocorticoids [ 92, 93].
Haemato-oncologists are increasingly faced with managing rrMM patients who experience multiple relapses and progressively shorter response durations, even with novel targeted agents.
Hypnozoites have the potential to seed multiple relapses, and it is not known whether prevention of just one of these by use of a slowly eliminated antimalarial will reduce the total number of relapses or simply delay the occurrence of the next relapse.
Eligibility for HDCT with ASCR required a histologically or tumour marker proven germ cell tumour, multiple relapse and/or refraction to prior chemotherapy, a Karnofsky index ⩾60% and an age ⩾18 years.
This incurable disease, which has a median survival of 5 years, poses the major challenge of multiple relapse [ 4, 5].
Certainly, in complicated multiple relapse patients, the use of FDG-PET has been shown to change the decision on therapy in 57% of cases [ 8].
This was surprising since TICs from other tumours have been shown to be resistant to various chemotherapeutics and the primary screen was conducted with NB TICs derived from a heavily-treated, multiple relapse patient (NB12).
